Genetics

Ancient DNA Study Reveals Prehistory of Southeast Asia

The first whole-genome analysis of ancient human DNA from Southeast Asia, defined as the area east of India and south of China, identifies at least three major waves of human migration into the region over the last 50,000 years, each shaping the genetics of Southeast Asia ‘to a remarkable extent.’ …

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Study: Natural Selection Still at Work in Humans

An international team of scientists from Australia, the Netherlands, Estonia and the United States has detected significant signatures of natural selection in the human genome that influence traits associated with fertility and heart function. Zeng et al detected signatures of natural selection in the genetic architecture of 23 complex traits. …

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Scientists Identify 124 New Genes that Determine Hair Color

Researchers have discovered 124 genes that play a major role in determining human hair color variation. The findings were published online this week in the journal Nature Genetics. Hysi et al identified 123 autosomal and one X-chromosome loci significantly associated with hair color. Image credit: Kristyna Matlachova. In order to …

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‘Junk’ DNA Plays Crucial Role in Holding Genome Together: Study

A new study published online in the journal eLife indicates that satellite DNA — commonly called ‘junk’ DNA — performs the vital function of ensuring that chromosomes bundle correctly inside the cell’s nucleus, which is necessary for cell survival; and this function appears to be conserved across many species. Jagannathan …

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New Genetic Cause of Posterior Polymorphous Corneal Dystrophy Discovered

A new genetic cause of an autosomal-dominant corneal endothelial dystrophy has been discovered in a study led by University College London scientists. Posterior polymorphous corneal dystrophy is a rare autosomal-dominant disorder, primarily affecting the corneal endothelium and Descemet membrane. Image credit: Pexels. Corneal endothelial dystrophies are a group of inherited …

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